Hepatitis C  
 

Definition

Hepatitis C is an infection caused by a virus that attacks the liver and leads to inflammation. Most people infected with the hepatitis C virus (HCV) have no symptoms. In fact, most people don't know they have the hepatitis C infection until liver damage shows up, decades later, during routine medical tests.

Hepatitis C is one of several hepatitis viruses and is generally considered to be among the most serious of these viruses. Hepatitis C is passed through contact with contaminated blood — most commonly through needles shared during illegal drug use.

Symptoms

Hepatitis C infection usually produces no signs or symptoms during its earliest stages. When signs and symptoms do occur, they may include:

·         Fatigue

·         Fever

·         Nausea or poor appetite

·         Muscle and joint pains

·         Yellowing of the skin and whites of the eyes (jaundice)

When to see a doctor

Make an appointment with your doctor if you have any signs and symptoms that worry you.

Causes

Hepatitis C infection is caused by the hepatitis C virus (HCV). HCV is spread when you come in contact with blood contaminated with the virus.

Risk factors

Your risk of hepatitis C infection is increased if you:

·         Are a health care worker who has been exposed to infected blood, such as may happen if an infected needle pierces your skin

·         Have ever injected illicit drugs

·         Have HIV

·         Received a piercing or tattoo in an unclean environment using unsterile equipment

·         Received a blood transfusion or organ transplant before 1992

·         Received clotting factor concentrates before 1987

·         Received hemodialysis treatments for a long period of time

·         Were born to a woman with a hepatitis C infection

 

Complications

Hepatitis C infection that continues over many years can cause significant complications, such as:

·         Scarring of the liver tissue (cirrhosis). After 20 to 30 years of hepatitis C infection, cirrhosis may occur. Scarring in your liver makes it difficult for your liver to function.

·         Liver cancer. A small number of people with hepatitis C infection may develop liver cancer.

·         Liver failure. A liver that is severely damaged by hepatitis C may be unable to function adequately

Tests and diagnosis

Screening for hepatitis C

Testing for hepatitis C infection in people who have a high risk of coming in contact with the virus may help doctors begin treatment or recommend lifestyle changes that may slow liver damage. This is recommended because hepatitis C infection often begins damaging the liver before it causes signs and symptoms.

People who may want to talk to their doctors about screening for hepatitis C infection include:

·         Anyone who has ever injected illicit drugs

·         Anyone with unexplained, unusual liver function test results

·         Babies born to mothers with hepatitis C

·         Health care and emergency workers who have been exposed to blood or accidental needle sticks

·         People with hemophilia who were treated with clotting factors before 1987

·         People who have ever undergone long-term hemodialysis treatments

·         People who received blood transfusions or organ transplants before 1992

·         Sexual partners of anyone diagnosed with hepatitis C infection

·         People with HIV infection

·         Anyone born from 1945 to 1965

Blood tests to diagnose hepatitis C

Blood tests may help to:

·         Determine whether you have the hepatitis C virus

·         Measure the quantity of the hepatitis C virus in your blood (viral load)

·         Evaluate the genetic makeup of the virus (genotyping), which helps determine your treatment options

Testing samples of liver tissue to determine severity of liver damage

Your doctor may also recommend a procedure to remove a small sample of liver tissue for laboratory testing. A liver biopsy can help determine the severity of the disease and guide treatment decisions. During a liver biopsy, your doctor inserts a thin needle through your skin and into your liver to remove the tissue sample.

Treatments and drugs

Treatment isn't always necessary

A diagnosis of hepatitis C infection doesn't necessarily mean you need treatment. If your doctor recommends no treatment, you'll undergo follow-up blood tests to monitor for liver problems.

Antiviral medications

Hepatitis C infection is treated with antiviral medications intended to clear the virus from your body. Your doctor may recommend a combination of medications taken over several weeks.

Throughout treatment your doctor will monitor your response to medications.

Antiviral medications can cause depression and flu-like signs and symptoms, such as fatigue, fever and headache. Some side effects can be serious enough that treatment must be delayed or stopped in certain cases.

Liver transplant

If your liver has been severely damaged, a liver transplant may be an option. During a liver transplant, the surgeon removes your damaged liver and replaces it with a healthy liver. Most transplanted livers come from deceased donors, though a small number come from living donors who donate a portion of their livers.

For people with hepatitis C infection, a liver transplant is not a cure. Treatment with antiviral medications usually continues after a liver transplant, since hepatitis C infection is likely to recur in the new liver.

Vaccinations to protect against other forms of viral hepatitis

Your doctor will likely recommend that you receive vaccines against the hepatitis A and B viruses. These are separate viruses that also can cause liver damage and complicate treatment of hepatitis C.

Lifestyle and home remedies

If you receive a diagnosis of hepatitis C, your doctor will likely recommend certain lifestyle changes. These measures will help keep you healthy longer and protect the health of others as well:

·         Stop drinking alcohol. Alcohol speeds the progression of liver disease.

·         Avoid medications that may cause liver damage. Review your medications with your doctor, including the over-the-counter medications you take. Your doctor may recommend avoiding certain medications.

·         Help prevent others from coming in contact with your blood. Cover any wounds you have and don't share razors or toothbrushes. Don't donate blood, body organs or semen, and advise health care workers that you have the virus.

Prevention

Protect yourself from hepatitis C infection by taking the following precautions:

·         Stop using illicit drugs. If you use illicit drugs, seek help.

·         Be cautious about body piercing and tattooing. If you choose to undergo piercing or tattooing, look for a reputable shop. Ask questions beforehand about how the equipment is cleaned. Make sure the employees use sterile needles. If employees won't answer your questions, look for another shop.

·         Practice safer sex if you choose to have sex. Don't engage in unprotected sex with multiple partners or with any partner whose health status is uncertain. Sexual transmission between monogamous couples may occur, but the risk is low.

Reference: Myoclinic.org

 




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